According to Bella Blisett in her book Ask. The 1000 Most Asked Questions About Beauty, Artefill, or Artecoll, is a natural collagen filler that, umlike Botox, has the advantage of not being absorbed by the body. Its effects are immediate and you’ll probably need only one or two shots to work in the long term.

This is great news since Botox usually lasts just three to four months. I don’t know about the cost of Artefill but it sounds liks something to look into.